How your Endocannabinoid System Works
The endocannabinoid system (ECS) is a biological system of neurotransmitters in the mammalian central and peripheral nervous systems. The ECS is involved in regulating a variety of physiological and cognitive processes including fertility, appetite, pain-sensation, mood, and memory. Your body makes its own cannabinoids in limited quantities, and plant-based sources (such as hemp-derived CBD) are known as phytocannabinoids.
CB1 & CB2 receptors and what they do
Two primary endocannabinoid receptors have been identified: CB1and CB2. CB1 receptors are primarily found in the brain, although they are also both present in the male and female reproductive organs. Current research shows that THC is specifically keyed to the CB1 site. Therefore it is responsible for the feeling of intoxication that is the most familiar aspect of cannabis. From a therapeutic standpoint, its most important effect is to modulate and moderate the perception of pain. Additionally, CB1 receptors are not present in the part of the brain that regulates heart rate and respiration, so unlike narcotics, there is no lethal dosage threshold for THC, allowing someone to consume as much is needed for palliative effects.
CB2 receptors are primarily found in the immune system, with the highest concentration located in the spleen. There is some evidence that the receptors might also be in the micro parts of the brain’s basal ganglia, or nerve bundles. The CB2 receptors are keyed to CBD and work as an anti-inflammatory agent. The immune-boosting functions of CB2 are far less understood as research into CBD is just really beginning. The benefits of CBD-rich medicine is one the most exciting and promising areas of cannabis medical research currently happening.